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PB: Contract voor 30 miljoen!

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Omlaag ↓

[verwijderd] 3 oktober 2008 18:01

Een mooi bericht voor de R&D afdeling die nu wel zo goed als volledig door de markt onder contract zal staan.
Ga zeker luisteren 2 november!

[verwijderd] 3 oktober 2008 18:02

Ongelofelijk, 30 mil extra op een geschatte jaar omzet van +- 320, extra order Q5 van 140 mil met marge van 40%. Dan zou je toch denken door de extra Cashflow inkomsten en misschien winst (wat naar mijn mening helemaal niets zegt over een bedrijf) de koers allang veel hoger had moeten staan ondanks kredit crises. Maar wat in het vat zit verzuurd niet?

eddy59 3 oktober 2008 18:23

Even geduld en dan als een raket omhoog, eind van dit jaar op € 16,00

[verwijderd] 3 oktober 2008 18:49

zolangerzamerhand wordt het tijd dat iemand de fundamentele feiten op een rijtje zet.
als crucell zelf meer producten op de markt zet en we weten omzet dan kan je aardig uitrekenen wat de winst wordt en wat aandeel moet doen.
dit geroep van x euro per dan, is meestal nergens op gebaseerd.
ik denk ook dat indien er een grote jongen is met geld, tja net nu, het voor crucell beter is om opgekocht te worden. ze hanessen te veel in mijn optiek van persbericht naar persbericht.
de aankoop van Berna was nog steeds een goede zet, omdat het cashflow genereert en organisatie verbeteringen geeft dus besparingen.
huidige management heeft toch ook wel wat problemen en straalt weinig consistentie en concrete realisatie van mooie plannen uit.
ik houd zenog maar ff maar ik ben er niet meer verliefd op. dat laatste is zowiezo niet slim. gaat tenslotte ook bij mij om de ROI
groet
en prettig weekend maar vast.
w

Sir Piet 4 oktober 2008 18:28

"beter om opgekocht te worden" onzin. Laten we hopen dat deze parel voor nederland behouden blijft.

josti5 4 oktober 2008 18:50

quote:
Sir Piet schreef:
"beter om opgekocht te worden" onzin. Laten we hopen dat deze parel voor nederland behouden blijft.

Never nooi nie Sir Piet, tenzij de ogen in Den Haag ook wat dit onderwerp betreft open gaan, en de Staat een aanmerkelijk belang (51%) neemt in Crucell.

Fantastisch voor de toekomst van Vadertje Financiële Staat en al haar onderdanen!!!

Laat de Yanks in pakweg 2016 maar flink overname-dokken, in plaats van hun smerige spelletjes op de beurs te spelen, en nu al de buit binnen te halen.

Ooit is de farmaceutische industrie uit Nederland verdwenen (de laatste Gist-restanten worden opgedoekt, Pharming: nou ja, Fornix: oeps), en momenteel ligt er weer de gouden Crubuy kans, om deze voor ons aller Nederland opnieuw te verwerven: voor slechts 350 miljoen liggen de Gouden Bergen op Nederland te wachten: toekomstige inkomsten op aardgasniveau, talloze enge ziektes in eigen Klink-hand, en veeeeeeeel meer renderend dan dat lowsy Fortis/ABN!

Hopelijk leest Bos deze posting...

maxen 10 oktober 2008 15:47

10/10/2008

www.cnn.com/2008/WORLD/africa/10/10/m...

South Africa: Mystery hemorrhagic fever kills 3

GENEVA (AP) -- -- The U.N. health agency says it is investigating a mystery disease that killed three people in the South African city of Johannesburg.

The World Health Organization says the disease appears to be a form of hemorrhagic fever.

It says tests have proved negative for Ebola, Lassa fever, Rift Valley fever, Marburg fever and other main types of hemorrhagic fever.

WHO spokesman Gregory Hartl says the first death on Sept. 13 was a tour guide who had fallen ill in Zambia before being evacuated to South Africa. Two further deaths on Sept. 30 and Oct. 4. involved a paramedic and a nurse who treated the woman.

Hartl said Friday that 121 people are being monitored and WHO hopes to receive further test results by Sunday.

flosz 10 oktober 2008 22:12

Ebola Vaccine in Sight?

By Noah Shachtman October 10, 2008 | 10:43:00 AMCategories: Chem-Bio, Medic!

I read The Hot Zone maybe a dozen years ago. And the story of an almost-outbreak of Ebola in Virginia still gives me the occasional bleeding-from-every-orifice nightmare. Which is why I'm glad to hear that the feds just handed out a pair of contracts to develop vaccines against the Ebola and Marburg viruses.
"The two hemorrhagic fever viruses are... are considered category A bioterrorism agents by the U.S. government," the Center for Infectious Disease Research & Policy notes. Both diseases are known for their high case-fatality rates, and there are no specific treatments or vaccines for Marburg and Ebola fevers."
The contracts, worth $52 million, are going to A Dutch firm, Crucell, and Maryland's Integrated BioTherapeutics. The company says its been working with the Army's Medical Research Institute of Infectious Diseases on a vaccine that already "provides broad protection in nonhuman primates." Hopefully, it'll work in humans. So I can sleep a little easier.
blog.wired.com/defense/2008/10/ebola-...

[verwijderd] 10 oktober 2008 22:15

quote:
Mar1 schreef:
Nog beneden de 11,- in kunnen stappen de zoveelste rit met Crucell?

Nog beneden de € 8 in kunnen stappen voor de zoveelste rit met Crucell??

flosz 14 oktober 2008 08:53

quote:
maxen schreef:
10/10/2008
www.cnn.com/2008/WORLD/africa/10/10/m...
South Africa: Mystery hemorrhagic fever kills 3
GENEVA (AP) -- -- The U.N. health agency says it is investigating a mystery disease that killed three people in the South African city of Johannesburg.
The World Health Organization says the disease appears to be a form of hemorrhagic fever.
It says tests have proved negative for Ebola, Lassa fever, Rift Valley fever, Marburg fever and other main types of hemorrhagic fever.
WHO spokesman Gregory Hartl says the first death on Sept. 13 was a tour guide who had fallen ill in Zambia before being evacuated to South Africa. Two further deaths on Sept. 30 and Oct. 4. involved a paramedic and a nurse who treated the woman.
Hartl said Friday that 121 people are being monitored and WHO hopes to receive further test results by Sunday.

No vaccine for killer virus
October 13, 2008, 05:45
The National Institute for Communicable Diseases (NICD) says there are no vaccines available for viral haemorragic fever in this country. Doctor Janusz Paweska was speaking in Johannesburg following the release of preliminary results of tests on the mysterious viral haemorragic fever which killed three people.

Authorities revealed that the victims died of a ''rodent-borne arena virus'' which is a type of viral haemorragic fever. The rodents, found in West Africa, can contaminate food or dust particles. Two people suspected to have viral haemorragic fever are still in isolation at the Morningside Medi-Clinic in Johannesburg. Paweska says there is a drug which has shown promising results - but only if diagnosed as soon as possible.

Meanwhile health experts have assured South Africans that they have no reason to worry about contracting the deadly rodent-borne arena virus from local rats. Yesterday the NICD and the Centre for Disease Control identified the arena virus related to the Lassa fever virus in West Africa as the reasons behind the death of the three people.

The arena virus causes chronic infection in certain types of wild rodents. The virus is carried in the urine of wild mice which can contaminate human food. Robert Swanepoel of the NICD says there is no indication that arena viruses which could cause disease in humans were present in South African rodents
www.sabcnews.com/south_africa/health/0,2172,178159,00.html

Arenavirus factsheet
www.cdc.gov/ncidod/dvrd/spb/mnpages/d...

flosz 31 oktober 2008 10:11

Friday, Oct. 31, 2008

Ebola vaccine under development in Germantown lab
Integrated BioTherapeutics co-founder says disease's threat could be reduced

Scientists in a Germantown laboratory are working to develop a vaccine against the deadly Ebola virus, a disease that reportedly has killed 1,200 people, mainly in African nations.
Integrated BioTherapeutics recently received a multimillion-dollar contract from the National Institute of Allergy and Infectious Diseases to boost its development efforts. Co-founder and chief scientific officer Javad Aman says Ebola and Marburg, a related, often lethal virus, could begin to recede as threats to humans in about 10 years, when he hopes the vaccine will become widely available. Ebola and Marburg are both found most commonly in sub-Saharan Africa.
"This is really important for public health and national security," said Aman, 50. "We feel very passionate about our work, no doubt about it."
Through relationships with other companies, including Becton Dickinson, Integrated's 11 employees also work on developing vaccines against staph and strep infections, plus antivirals against viral hemorrhagic fevers, according to its Web site.
Aman worked to develop an Ebola vaccine for seven years at the Army Research Institute for Infectious Diseases at Fort Detrick in Frederick. He and a colleague, Kelly L. Warfield, 32, launched Integrated BioTherapeutics in 2005.
The privately held company, named Best Life Science Company in the Maryland Incubator Company of the Year awards in June, started operations in 2006 with a $50,000 grant from the Maryland Technology Development Corp. It moved this year from the Frederick Innovative Technology Center incubator to its quarters on Seneca Meadows Parkway, in a building it shares with Avalon Pharmaceuticals.
Work now includes testing the vaccine and preparing it for manufacture and distribution, he said. The new federal contract calls for the company to receive an initial $22 million, with $43.2 million to be paid upon successful completion of later phases of the project.
Integrated BioTherapeutics is not the only company to receive a federal contract this month to develop Ebola and Marburg vaccines. Crucell, a publicly traded Dutch biopharmaceutical company, won a deal worth up to $70 million from the National Institute of Allergy and Infectious Diseases to advance its efforts, according to a Crucell statement.
Aman's pride in what he considers a breakthrough discovery is evident as he discusses the vaccine. The rewards will be great once the elaborate clinical trials and government approval process are complete, he said.
Warfield is equally passionate.
"When you're a scientist, this is what you really want to do, something that benefits all mankind," she said.
Careless handling of infected monkeys by humans and accidents in biotechnology laboratories is the main threat posed by Ebola to people in developed countries, although the virus is also seen as a potential bioterror agent, according to the World Health Organization. But most of the 1,850 reported cases and 1,200 deaths recorded since Ebola's discovery in 1976 through 2005 have come among Africans in mid-continent nations.
The disease kills 30 percent to 90 percent of humans infected by it, preceded by symptoms that include the sudden onset of fever, intense weakness, muscle pain, headache and sore throat. Patients with advanced cases suffer vomiting, diarrhea, rash, impaired kidney and liver function and, in some cases, internal and external bleeding.
Anyone who read Richard Preston's 1995 non-fiction best-seller "The Hot Zone: A Terrifying True Story," which tracks the virus from its African victims to Fort Detrick, where researchers and biohazard teams worked to contain an outbreak, might expect a similarly tense atmosphere at Integrated BioTherapeutics. But scientists and technicians in one of the company's laboratories appeared relaxed as they worked last week. Aman and Warfield said the employees do not face any risk from the virus.
Experiments using the virus itself are conducted only at Fort Detrick, they said. Work at the Germantown laboratory includes testing the vaccine on mice that have not been infected. Aman said the effectiveness of the vaccine is checked by examining how the immune systems of animals react after receiving the vaccine.
Warfield said two Russian scientists accidentally infected themselves on two separate occasions a few years ago and died from the virus. Another scientist, at Fort Detrick, was unharmed in 2004 after an accidental needle prick from a syringe containing the virus, she said.
Warfield said she was never afraid during the six years she spent at Fort Detrick, a period that included seeing animals that had been infected by Ebola during experiments.
"I have a family of four children," she said. "You just have to be aware of the dangers you're taking or you shouldn't be working there."
www.gazette.net/stories/10312008/busi...

flosz 2 januari 2009 15:50

Philippines: Ebola-Reston Virus Found in Pigs.

This is the first time, the Ebola-Reston virus has been found in pigs. The virus was discovered in the Philippines after field investigations were conducted and sample collections were taken.
The Ebola-Reston virus has been discovered in the Philippines.The discovery was made after the Bureau of Animal Industry (BAI), Department of Agriculture of the Philippines conducted field investigations and sample collections.

This work was undertaken because of suspected outbreaks of Porcine Reproductive and Respiratory Syndrome (PRRS) affecting several swine production areas.

The discovery of the Ebola-Reston virus in pigs,which is a first, requires further medical, veterinary and biological research. Testing animal handlers and wildlife for the presence of the Ebola-Reston virus will be helpful to understand how pigs may have become infected and to learn more about a potential spill over to humans. It will probably take weeks or even months to obtain the first results of this analysis.

To date, there are no reports of sick or ailing people among those having had contact with infected pigs according to the Philippine Ministry of Health and the Bureau of Animal Industry.

There were incidents of pig illness and deaths on the farms where Ebola-Reston infected swine were bred and raised. It is possible other microorganisms isolated from sick and dying swine were the cause of elevated mortality rather than the Ebola-Reston virus.
www.digitaljournal.com/article/264295
***********************
KINSHASA, Congo: An Ebola virus outbreak has killed 11 people in western Congo, the health minister said.
A total of 35 people have been infected in Kaluemba, Western Kasai province, where the epidemic began in late November, Health Minister August Mopipi said.
Suspected cases of the highly contagious disease have also been identified in neighboring villages, Mopopi said.
Laboratory tests in both Gabon and Congo's National Institute for Biomedical Research confirmed Ebola in the 11 deaths, he said.
The World Health Organization has confirmed only two Ebola cases, however, and said other diseases were likely involved.

www.iht.com/articles/ap/2008/12/30/af...

Uganda on alert as Ebola fever breaks out in DR Congo
news.xinhuanet.com/english/2009-01/01...

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